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Intracellular Ca 2+ handling and myofibrillar Ca 2+ sensitivity are defective in single muscle fibres of aged humans
Author(s) -
Cheng Arthur J.,
Chaillou Thomas,
Gineste Charlotte,
Schlittler Maja
Publication year - 2015
Publication title -
the journal of physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.802
H-Index - 240
eISSN - 1469-7793
pISSN - 0022-3751
DOI - 10.1113/jp270960
Subject(s) - myofibril , myofilament , myosin , tropomyosin , biophysics , troponin , skeletal muscle , chemistry , endoplasmic reticulum , muscle contraction , intracellular , sarcomere , calcium , crossbridge , medicine , sarcopenia , isometric exercise , actin , myocyte , anatomy , biology , biochemistry , myocardial infarction