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Extremely low electrical current generated by porcine small intestine smooth muscle alters bacterial autolysin production
Author(s) -
Kruszewska Danuta,
Podgurniak Paweł,
Ljungh Åsa,
Sebastian Aleksandra,
Larsson Lennart,
ZajdelDa̧browska Jolanta,
Pierzynowski Stefan G.
Publication year - 2005
Publication title -
experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0958-0670
DOI - 10.1113/expphysiol.2005.030858
Subject(s) - autolysin , bacteria , peptidoglycan , lactic acid , in vivo , bacterial cell structure , microbiology and biotechnology , in vitro , biology , biophysics , chemistry , biochemistry , genetics
The effect of extremely low electrical currents, identical to those generated by the gut smooth muscle, on bacterial autolysin production in vitro was tested in the present study. When stimulated with these electrical currents, the bacteria Pediococcus pentosaceus 16:1 produced groups of peptidoglycan hydrolases that differed from those produced by the unstimulated (control) bacteria. The autolysins synthesized by the P. pentosaceus 16:1 under extremely low electrical currents were effective against peptidoglycans from the cell walls of various lactic acid bacteria strains, whereas the autolysins from the control bacteria acted exclusively against P. pentosaceus 16:1 cell walls. Thus, it can be predicted that in vivo the electrical currents generated by the intestinal smooth muscles, which can be recorded as the myoelectrical migrating complexes, could regulate lactic acid bacteria strain growth in the gut.