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Non‐adrenergic, non‐cholinergic reflex secretion of parotid saliva in rats elicited by mastication and acid applied on the tongue
Author(s) -
Ekstrom J
Publication year - 1998
Publication title -
experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0958-0670
DOI - 10.1113/expphysiol.1998.sp004150
Subject(s) - saliva , cholinergic , mastication , endocrinology , medicine , reflex , atropine , tongue , adrenergic , parotid gland , secretion , adrenergic antagonist , sham feeding , antagonist , chemistry , receptor , pathology , dentistry
Chewing and acid on the tongue evoked a flow of saliva from the duct‐cannulated parotid gland of the conscious rat despite pretreatment with atropine and adrenoceptor antagonists. This non‐adrenergic, non‐cholinergic (NANC) response depended on an intact parasympathetic innervation and was abolished by a tachykinin antagonist. The present findings are consistent with a physiological role for the secretory NANC mechanisms of the salivary glands.