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Identification of projections from the central nucleus of the amygdala to the paraventricular nucleus of the hypothalamus which are immunoreactive for corticotrophin‐releasing hormone in the rat
Author(s) -
Marcilhac A,
Siaud P
Publication year - 1997
Publication title -
experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0958-0670
DOI - 10.1113/expphysiol.1997.sp004022
Subject(s) - hypothalamus , nucleus , amygdala , endocrinology , medicine , central nucleus of the amygdala , biology , central nervous system , hormone , neuroscience , chemistry
Corticotrophin‐releasing hormone (CRH) immunoreactivity was detected in neurons of the central nucleus of the amygdala that were retrogradely labelled by injection of a fluorescent tracer (True Blue) into the paraventricular nucleus of the hypothalamus (PVN). The double‐labelled neurons were located mainly in the medial subdivision of the central nucleus and appeared to comprise less than one‐fifth of the descending pathway. These results suggest that CRH may act as a neurotransmitter in the amygdalo‐hypothalamic pathway.