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Separation of tubular electrical activity in amphibian skeletal muscle through temperature change
Author(s) -
Padmanabhan N,
Huang CL
Publication year - 1990
Publication title -
experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0958-0670
DOI - 10.1113/expphysiol.1990.sp003452
Subject(s) - amphibian , skeletal muscle , biophysics , chemistry , biology , anatomy , ecology
The effect of temperature on the form of the propagated action potential was investigated in frog skeletal muscle fibres. Increasing the temperature decreased the duration of the initial overshoot but a hump then appeared during a more prominent after‐depolarization. Finally, at 28‐30 degrees C, the after‐depolarization was either noticeably enlarged or entirely absent. This all‐or‐none failure of tubular conduction suggests that excitation of the tubular membrane takes place through regenerative activity rather than graded electrotonic spread of depolarization. However, it is consistent with a partial electrical isolation of the tubular lumina, possibly through the access resistance proposed in earlier theoretical models for muscle membrane.