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The effects of changes in laryngeal airway CO2 concentration on genioglossus muscle activity in the anaesthetized cat
Author(s) -
Nolan P,
Bradford A,
O'Regan RG,
McKeogh D
Publication year - 1990
Publication title -
experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0958-0670
DOI - 10.1113/expphysiol.1990.sp003403
Subject(s) - genioglossus , larynx , medicine , respiration , reflex , anesthesia , airway , pharyngeal muscles , superior laryngeal nerve , respiratory system , laryngeal paralysis , ventilation (architecture) , electromyography , anatomy , laryngoscopy , intubation , physical medicine and rehabilitation , mechanical engineering , engineering
In the anaesthetized cat the larynx was isolated in situ, artificially ventilated and used to assess reflex effects exerted by respiration‐related laryngeal stimuli on genioglossus electromyographic activity (Gg EMG) and respiratory frequency (RF). Phasic Gg EMG was not observed when the larynx was unventilated but was evoked, with a concurrent decrease in RF, when negative pressures or oscillatory pressures similar to those of normal ventilation were applied to the larynx. Increases in laryngeal airway CO2 concentration also enhanced Gg EMG and reduced RF. All reflex effects were abolished by bilateral section of the superior laryngeal nerves. We propose that negative intralaryngeal pressure and CO2 may act together to restore pharyngeal patency during obstructive apnoea.