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A COMPARISON OF CONTRACTILE FUNCTION IN LARGE AND SMALL PULMONARY ARTERIAL VESSELS OF THE RAT
Author(s) -
Leach Richard M.,
Twort Charles H. C.,
Cameron Ian R.,
Ward Jeremy P. T.
Publication year - 1989
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0144-8757
DOI - 10.1113/expphysiol.1989.sp003366
Subject(s) - myograph , pulmonary vessels , cardiology , vascular resistance , anatomy , pulmonary vasculature , pulmonary artery , medicine , chemistry , biomedical engineering , materials science , artery , hemodynamics
The contractile function of rat pulmonary arterial vessels, ranging in internal diameter from 100 to 2000 µm, was studied in vitro using a small vessel myograph. It was found that vessels with a diameter of 200‐400 µm produced considerably more force for a given intervention than those either smaller (〈100‐2000 µm) or larger (400‐2000 µm). It is suggested that these vessels may play an important role in the generation of pulmonary vascular resistance.