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THE DISTRIBUTION OF β‐ADRENOCEPTORS IN HUMAN CERVIX
Author(s) -
Whitaker E. M.,
Nimmo A. J.,
Morrison J. F. B.,
Griffin N. R.,
Wells M.
Publication year - 1989
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0144-8757
DOI - 10.1113/expphysiol.1989.sp003309
Subject(s) - distribution (mathematics) , cervix , medicine , mathematics , cancer , mathematical analysis
The distribution of βadrenoceptors in sections of human cervix taken at the proliferative phase of the menstrual cycle was studied using light‐microscopic autoradiography. The radioligand [ 125 I]iodo‐cyanopindolol ( 125 ICYP) was used to identify specific binding sites. Moderate density of labelling by 125 ICYP was seen over smooth muscle and blood vessels. The most intense labelling, however, was seen over glands and surface columnar epithelium. The association of β‐adrenoceptors with glands and surface columnar epithelium suggests a possible adrenergic regulation of secretory function in the cervix.