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EFFECT OF DISTENSION OF THE URINARY BLADDER ON EFFERENT CARDIAC SYMPATHETIC NERVE FIBRES WHICH RESPOND TO STIMULATION OF ATRIAL RECEPTORS
Author(s) -
Hassan A. A. M.,
Hicks M. N.,
Walters G. E.,
Mary D. A. S. G.
Publication year - 1987
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0144-8757
DOI - 10.1113/expphysiol.1987.sp003035
Subject(s) - distension , efferent , baroreceptor , stimulation , medicine , urinary bladder , carotid sinus , chemoreceptor , urinary system , endocrinology , anesthesia , receptor , heart rate , blood pressure , afferent
The effect of distension of the urinary bladder on the activity in the efferent cardiac sympathetic nerves which responded to stimulation of atrial receptors or those which responded to stimulation of carotid baroreceptors or chemoreceptors, was studied in dogs anaesthetized with chloralose; the urinary bladder was distended with warm saline, small balloons were positioned at the right pulmonary vein‐atrial junctions and distended with 1 cm 3 saline, and the carotid sinuses were vascularly isolated and perfused with blood at constant flow. The efferent cardiac sympathetic nerve fibres which responded to stimulation of carotid baroreceptors and chemoreceptors by a decrease in activity always responded with an increase in activity in response to distension of the urinary bladder. In contrast, in those efferent cardiac sympathetic nerve fibres which did not respond to an increase in carotid sinus pressure, but responded to stimulation of atrial receptors by an increase in activity, distension of the urinary bladder neither caused a significant change in activity nor produced a reproducible pattern of response. It is concluded that the efferent cardiac sympathetic nerve fibres which respond to stimulation of atrial receptors are separate from those which respond to distension of the urinary bladder.