Premium
RETROGRADE INFUSION OF BLOOD INTO A PULMONARY VEIN PROMOTES NATRIURESIS IN ANAESTHETIZED DOGS
Author(s) -
Sutton P. M. I.,
Abed J. S. M.,
Nashat F. S.
Publication year - 1986
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0144-8757
DOI - 10.1113/expphysiol.1986.sp003021
Subject(s) - natriuresis , central venous pressure , blood pressure , medicine , pulmonary vein , cardiology , anesthesia , excretion , left atrial pressure , vein , heart rate , atrial fibrillation
Retrograde infusion of blood into a pulmonary vein raised the pressure by 0·5‐1 kPa in the cannulated vein. There were no changes in heart rate, arterial blood pressure, left atrial pressure, right atrial pressure or the pressure in the other pulmonary veins. The rise in pulmonary venous pressure was associated with an increase in urinary sodium concentration and excretion. However, there was no change in urine volume. The natriuresis was abolished by cooling the vagi to 9 °C. It is argued that receptors up‐stream in the pulmonary veins themselves may be involved in the increase in sodium excretion that follows a rise in left atrial pressure.