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FREE INTRACELLULAR MAGNESIUM CONCENTRATION IN FERRET VENTRICULAR MUSCLE MEASURED WITH ION SELECTIVE MICRO‐ELECTRODES
Author(s) -
Blatter L. A.,
McGuigan John A. S.
Publication year - 1986
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0144-8757
DOI - 10.1113/expphysiol.1986.sp003005
Subject(s) - electrode , calibration curve , magnesium , extrapolation , ion , calibration , analytical chemistry (journal) , chemistry , materials science , penetration (warfare) , detection limit , chromatography , metallurgy , mathematics , mathematical analysis , statistics , organic chemistry , operations research
The free Mg concentration ([Mg] i ) was measured in ferret ventricular muscle using single‐barrelled Mg‐sensitive micro‐electrodes. The electrodes were calibrated in solutions containing the [K] i and [Na] i measured in this tissue. In thirteen measurements from seven experiments conforming to strict criteria for calibration and penetration the estimated mean [Mg] i was 0·4 mmol/l. This is to be regarded as an upper limit since it was estimated by linear extrapolation of the calibration curve.