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CARDIOVASCULAR CHANGES ELICITED BY VAGAL GASTRIC AFFERENTS IN THE RAT
Author(s) -
Grundy D.,
Davison J. S.
Publication year - 1981
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0144-8757
DOI - 10.1113/expphysiol.1981.sp002560
Subject(s) - efferent , distension , cholinergic , vagus nerve , gastric distension , afferent , heart rate , stomach , blood pressure , medicine , inhibitory postsynaptic potential , vagal tone , baroreflex , vagotomy , autonomic nervous system , endocrinology , stimulation
Cardiovascular changes elicited by gastric distension in the urethane anaesthetized rat are described. Heart rate changes were mediated via a vago‐vagal pathway with ‘in‐series’ tension receptors in the stomach wall providing the afferent input and cholinergic cardio‐inhibitory fibres forming the efferent pathway. Blood pressure changes occurred independently of the heart rate changes; the main afferent pathway was again vagal but the efferent outflow was non‐cholinergic and probably sympathetic.