The Role of Cation‐Activated ATPases in Transmitter Release from the Rat Iris | Zendy

Reading H. W. | Zendy; Isbir Turgay | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

The Role of Cation‐Activated ATPases in Transmitter Release from the Rat Iris

Author(s) -

Reading H. W.,

Isbir Turgay

Publication year - 1980

Publication title -

quarterly journal of experimental physiology and cognate medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.925

H-Index - 101

eISSN - 1469-445X

pISSN - 0033-5541

DOI - 10.1113/expphysiol.1980.sp002495

Subject(s) - atpase , chemistry , intracellular , biophysics , calcium , enzyme , ion pump , iris (biosensor) , biochemistry , ion , biology , organic chemistry , computer security , computer science , biometrics

Release of noradrenaline (NA) from isolated rat iris during perfusion in K + ‐free medium was confirmed. Direct biochemical measurement of different cation‐activated ATPases did not reveal any definite relationship between Na + K + ATPase and NA release. A significant increase in Ca ++ Mg ++ ATPase activity was found on termination of NA release obtained by reintroduction of K+ to the medium. Criticism of the model for studying enzymatic control of transmitter release under physiological conditions is presented. It is suggested that removal of intracellular Ca ++ ions by a calcium pump is directly associated with termination of transmitter release.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research