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CHOLINE ACETYLTRANSFERASE ACTIVITY IN RAT SALIVARY GLANDS AFTER CELLULOSE RICH DIET OR TREATMENT WITH AN ATROPINE‐LIKE DRUG
Author(s) -
Ekström J.
Publication year - 1974
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1974.sp002261
Subject(s) - choline acetyltransferase , atropine , endocrinology , acetylcholine , medicine , enzyme assay , choline , salivary gland , drug , parotid gland , chemistry , submaxillary gland , enzyme , pharmacology , biochemistry , pathology
When rats are fed on dry, cellulose rich diet the choline acetyltransferase activity of the parotid gland increases, provided the auriculo‐temporal nerve is intact. Dryness of the oral mucosa produced by atropinization is also followed by an increase in enzyme activity of the gland. It is suggested that the increased activity of the acetylcholine‐synthesizing enzyme is due to enhanced traffic of secretory impulses in the para‐sympathetic nerves to the gland, reflexly elicited by the two kinds of treatment.