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SECRETORY ACTIVITY OF THE SUBMAXILLARY GLAND IN PREPUBERAL AND ADULT RATS OF BOTH SEXES
Author(s) -
Perec C.,
Bramuglia N.
Publication year - 1971
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1971.sp002097
Subject(s) - pilocarpine , submaxillary gland , endocrinology , medicine , methacholine , submandibular gland , stimulation , chorda , body weight , taste , chemistry , respiratory disease , food science , lung , epilepsy , psychiatry
The secretory responses of the submaxillary gland of prepuberal and adult rats of both sexes were studied by nerve stimulation and by giving sialagogues. The maximal secretory capacity per unit weight of gland was greater in adult males than in females, by 34 per cent after chorda‐lingual nerve stimulation and by 38 per cent after giving pilocarpine. The threshold dose of methacholine seemed less in prepuberal than in adult rats, but the threshold doses of sympathomimetic agents were similar in all groups. The response of the adult male's gland to methacholine (10 µg per kg body weight) was greater than that of the adult female's gland, both when measured per gland and when calculated per unit weight of gland.