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EFFECTS OF AGE AND ENVIRONMENTAL TEMPERATURE ON THE JUXTAGLOMERULAR APPARATUS OF HOUSE MICE
Author(s) -
Barnett S. A.,
Macadam R. F.
Publication year - 1971
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1971.sp002093
Subject(s) - juxtaglomerular apparatus , cytoplasm , endocrinology , medicine , biology , chemistry , renin–angiotensin system , microbiology and biotechnology , blood pressure
The kidneys of wild house mice, Mus musculus, L., aged 16, 28 and 100 weeks, were examined histologically, with special reference to the state of the juxtaglomerular apparatus (JGA). Some of the mice were kept in an environment at 21°C, others at −3°C. The percentage of glomeruli with JGAs containing cells with granulated cytoplasm was unaffected by environmental temperature, but declined with age. The decline was not related to the presence of inflammatory lesions or glomerular sclerosis.