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CHOLINESTERASE IN THE SUBMAXILLARY GLAND OF THE RAT AFTER SYMPATHETIC DENERVATION
Author(s) -
Nordenfelt Ivar
Publication year - 1968
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1968.sp001945
Subject(s) - submaxillary gland , denervation , cholinesterase , methacholine , medicine , endocrinology , cholinergic , sympathectomy , chemistry , respiratory disease , lung
Cholinesterase activities have been estimated manometrically in submaxillary glands of the rat after postganglionic sympathetic denervation. In denervated glands there is a significant increase of the break down of the two substrates studied, methacholine chloride and benzoylcholine chloride. This finding is considered to support the hypothesis that in the glands there is collateral sprouting of cholinergic fibres after degeneration of adjacent sympathetic neurones.