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ACETYLCHOLINE SYNTHESIS IN REINNERVATED SALIVARY GLANDS
Author(s) -
Nordenfelt Ivar,
Perec Carlos
Publication year - 1967
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1967.sp001895
Subject(s) - reinnervation , acetylcholine , submandibular gland , parotid gland , submaxillary gland , medicine , endocrinology , salivary gland , sublingual gland , chemistry , parasympathetic nervous system , anatomy , autonomic nervous system , pathology , heart rate , blood pressure
The synthesis of acetylcholine and the sensitivity towards sialagogue agents were studied in the submaxillary gland of the cat after crushing the preganglionic parasympathetic fibres and in the parotid gland of the rabbit after crushing the postganglionic parasympathetic fibres. The first signs of reinnervation in the cat's submaxillary gland were found after about two months, as seen by a decrease of supersensitivity and a slight increase in choline acetylase activity. Complete reinnervation varied very much but seemed to occur within a year. Reinnervation of the postganglionically denervated rabbit parotid gland was slower and much less complete.