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THE ROLE OF THE LYMPHATIC SYSTEM IN THE ABSORPTION OF WATER FROM THE INTESTINE OF THE RAT
Author(s) -
Barrowman J.,
Roberts K. B.
Publication year - 1967
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1967.sp001881
Subject(s) - lymphatic system , lymph , tonicity , tritiated water , chemistry , lumen (anatomy) , saline , ingestion , isotonic saline , absorption (acoustics) , anatomy , medicine , pathology , materials science , physics , nuclear physics , composite material , tritium
The flow and composition of lymph in the cisterna chyli and mesenteric lymphatic vessel of the restrained conscious rat has been studied in relation to the ingestion of 5 ml. of water and isotonic saline. In both cases the lymph flow increases and the protein concentration of the lymph falls; the time relationships are, however, different. When water is taken, the response begins in a few minutes and is over in 30 minutes; when saline is taken, the response begins in 15 minutes and is over in 60 minutes. The excess amount of lymph recovered during the responses is about 0·8 ml. These studies, and studies with tritiated water, suggest that during the first 10 minutes after rats drink water there is a transient bulk flow of fluid from the intestinal lumen into the intestinal lymphatics. The intestinal lymphatics seem to act as an overflow system during the absorption of hypotonic fluid.