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CHOLINE ACETYLASE IN SALIVARY GLANDS OF THE CAT AFTER SYMPATHETIC DENERVATION
Author(s) -
Nordenfelt Ivar
Publication year - 1965
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1965.sp001769
Subject(s) - superior cervical ganglion , medicine , denervation , endocrinology , atropine , choline , sympathetic trunk , parasympathetic nervous system , sympathetic denervation , ganglion , chemistry , sympathectomy , biology , anatomy , autonomic nervous system , heart rate , blood pressure
The choline acetylase activity of the cat's submaxillary and parotid glands has been found to increase after excision of the superior cervical ganglion. Both concentration and total activity were significantly changed. The enzyme increase did not occur if only the preganglionic sympathetic trunk had been sectioned. The increase of choline acetylase was found to be dependent on the presence of intact pre‐and postganglionic parasympathetic neurones. The enzyme change appeared, however, even if the glandular cells were made inactive with the atropine‐like substance Hoechst 9980.