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THE ACCURACY OF THE INDICATOR ABSORPTION METHOD OF MEASURING MAMMARY BLOOD FLOW BY THE FICK PRINCIPLE
Author(s) -
Rasmussen F.,
Linzell J. L.
Publication year - 1964
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1964.sp001722
Subject(s) - blood flow , fick principle , absorption (acoustics) , distribution (mathematics) , flow (mathematics) , chemistry , biomedical engineering , mechanics , materials science , mathematics , medicine , physics , hemodynamics , cardiac output , mathematical analysis , composite material
The distribution and fate of antipyrine after injection into the teat of goats has been determined and the blood flow, calculated on the Fick principle from uptake from the tissue, compared with the blood flow measured by other methods. In both conscious and anæsthetized animals and in perfused glands the antipyrine absorption method was usually accurate but occasionally overestimated the flow. The reasons for this and the limitations of the method are discussed.