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THE EFFECT OF GUANETHIDINE ON SODIUM TRANSPORT ACROSS THE ISOLATED FROG SKINT
Author(s) -
Baba W. I.,
Smith A. J.
Publication year - 1964
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1964.sp001719
Subject(s) - guanethidine , frog skin , sodium , chemistry , medicine , biophysics , endocrinology , biology , organic chemistry , stimulation
Guanethidine may cause fluid retention when it is used to treat hypertension in man. The possibility that this is due to an effect on sodium transport is examined in experiments on isolated frog skin. Guanethidine consistently increased the rate of active sodium transport through the skin.