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A COMPARISON OF THE OXYGEN AFFINITY OF MATERNAL AND FETAL BLOOD OF THE MACACA MULATTA
Author(s) -
Behrman Richard E.,
Heller Christopher J.,
Battaglia Frederick C.,
Hellegers Andre E.
Publication year - 1963
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1963.sp001663
Subject(s) - fetus , oxygen , oxygen tension , oxygen–haemoglobin dissociation curve , oxygen saturation , chemistry , andrology , saturation (graph theory) , biology , medicine , pregnancy , mathematics , combinatorics , genetics , organic chemistry
Constants relating the oxygen tension, percentage oxygen saturation and pH in the blood of maternal and fetal Macaca Mulatta (Rhesus) monkeys have been determined. Half saturation of the blood with oxygen is obtained at PO 2 's of 27·0 and 16·0 mm. of mercury in maternal and fetal blood respectively, at pH 7·40. The effect of pH changes upon the oxygen dissociation curves, and the slopes of these curves, were found to be identical in maternal and fetal blood. A comparison of the oxygen affinities of these bloods was made with those of other species, and the differences discussed.