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SOME OBSERVATIONS ON THE ERYTHROCYTE‐PIGMENT RELATIONSHIPS IN NEONATAL BLOOD AND MARROW
Author(s) -
Breathnach Caoimhghin S.
Publication year - 1962
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1962.sp001585
Subject(s) - cord blood , red cell , pigment , red blood cell , chemistry , andrology , biology , immunology , medicine , biochemistry , organic chemistry
Direct independent measurement of the percentage proportion of fœtal and adult erythrocytes and hæmoglobin as well as of the red cell diameters have been made on five samples of cord blood, and a fœtal marrow smear has been examined after differential elution. When cell capacity is taken into account the difference between the percentage fœtal erythrocytes and percentage fœtal hæmoglobin in cord blood in many cases largely disappears. In two out of five cases, in fact, the fœtal cell capacity and the fœtal pigment percentage coincided, but in one case the disparity remained when the capacity correction was made. It may be said, therefore, that in some though not in all cases hæmoglobin mixtures are not found in the one cell and each pigment has its own package. It is not permissible to assign morphologically discrete sites of production to fœtal and adult hæmoglobins, one is not formed exclusively in the liver, nor is the other the sole medullary product.