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AN ANALYSIS OF ACTIVE AND PASSIVE EFFECTS ON THE PULMONARY VASCULAR BED IN RESPONSE TO PULMONARY NERVE STIMULATION
Author(s) -
de Burgh Daly I.
Publication year - 1961
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1961.sp001542
Subject(s) - bronchoconstriction , vascular resistance , hypoxic pulmonary vasoconstriction , medicine , stimulation , vasoconstriction , constriction , nerve stimulation , lung , cardiology , anesthesia , hemodynamics , airway
In an isolated innervated perfused left lung preparation of the dog the calculated pulmonary vascular resistance overlapped the upper limit of the range reported by others for normal resting animals. The increase in pulmonary vascular resistance in response to stimulation of pulmonary nerves in which pulmonary vasoconstrictor fibres and bronchoconstrictor fibres are intermingled was due to vasoconstriction in the pulmonary vascular bed proper. This response was not appreciably altered or influenced by passive effects due to accompanying bronchoconstriction or changes in the bronchial circulation.