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THE ELECTROLYTE CONCENTRATION OF HUMAN GASTRIC SECRETION
Author(s) -
Strong J. A.,
Cameron D.,
Riddell M. J.
Publication year - 1960
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1960.sp001428
Subject(s) - hydrochloric acid , potassium , secretion , sodium , histamine , medicine , electrolyte , stimulation , chemistry , gastric acid , gastric secretion , endocrinology , stomach , chloride , inorganic chemistry , organic chemistry , electrode
The secretion by the stomach of hydrochloric acid, sodium, potassium and chloride has been studied in normal human subjects and in patients suffering from peptic ulcer. A close inverse relationship was demonstrated between the concentration of acid and sodium, and a direct relationship between potassium concentration and the rate of secretion of gastric juice. It is suggested that H and Na ions may share a secretory pathway, and that K concentration represents a part of the process of water secretion. These findings were consistent in over 300 samples of gastric juice, obtained without stimulation, and after stimulation with histamine or insulin.