THE INFLUENCE OF CARBON DIOXIDE AND pH ON THE ELECTROCARDIOGRAM OF THE ISOLATED PERFUSED HEART | Zendy

Trethewie E. R. | Zendy; Hodgkinson Margaret M. | Zendy

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THE INFLUENCE OF CARBON DIOXIDE AND pH ON THE ELECTROCARDIOGRAM OF THE ISOLATED PERFUSED HEART

Author(s) -

Trethewie E. R.,

Hodgkinson Margaret M.

Publication year - 1955

Publication title -

quarterly journal of experimental physiology and cognate medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.925

H-Index - 101

eISSN - 1469-445X

pISSN - 0033-5541

DOI - 10.1113/expphysiol.1955.sp001092

Subject(s) - bicarbonate , carbon dioxide , cardiology , u wave , electrolyte , medicine , electrocardiography , chemistry , anesthesia , organic chemistry , electrode

1. In the isolated cat's heart an increased CO 2 content of the perfusing fluid is associated with heightening of the T wave of the electrocardiogram when the electrolyte composition of the perfusing fluid is kept constant apart from bicarbonate change. 2. Under similar conditions a reduced CO 2 content is associated with a fall in the T wave potential. 3. The coronary flow changes in the same direction with the T wave, but equivalent changes in coronary flow alone do not cause similar changes in the T wave. 4. The significance of these findings is discussed.

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