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A QUANTITATIVE METHOD FOR MEASURING RED CELL CONTENT OF TISSUES IN VIVO
Author(s) -
Delorme E. J.
Publication year - 1953
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1953.sp001006
Subject(s) - red cell , spleen , in vivo , cell , red blood cell , kidney , cortex (anatomy) , biology , pathology , anatomy , chemistry , endocrinology , medicine , immunology , biochemistry , neuroscience , microbiology and biotechnology
1. Average in vivo values for red cell allocation in liver, spleen, kidney, gut and muscle in dogs have been obtained by an appropriate red cell labelling technique and expressed in numbers of red blood corpuscles per cubic millimetre of tissue. 2. The changes in red cell content observed in these tissues when the animal is bled are discussed and the importance of gradual red cell accumulation in muscle is pointed out. When blood is re‐infused after a prolonged period of oligæmia, general engorgement is noted in all tissues studied, with the exception of the spleen which remains relatively ischæmic. 3. When specific areas of contralateral frontal cortex are stimulated in the monkey, rapid but transitory increases in red cell content of muscle occur.