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NOTE UPON THE STABILITY OF THE RATE OF PARAAMINO HIPPURATE FORMATION OF RAT LIVER AND KIDNEY SLICES AND OF OXYGEN CONSUMPTION IN VITRO AFTER BURNING
Author(s) -
van Bekkum D. W.,
Peters R. A.,
Lathe G. H.
Publication year - 1950
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1950.sp000956
Subject(s) - chemistry , glycine , benzoic acid , kidney , significant difference , oxygen , in vitro , urine , medicine , endocrinology , amino acid , biochemistry , zoology , biology , organic chemistry
1. No significant difference in rate of formation of PAH, and in Qo 2 of liver and kidney slices from rats, has been found between unburned and burned animals at the height of the nitrogen loss in the urine. 2. Para‐amino benzoic acid with and without added glycine significantly depresses the Qo 2 of liver slices from both burned and unburned animals. 3. Glucose reduces the Qo 2 of liver slices from unburned animals, and lactate significantly increases it in burned animals, but no significant difference is found between burned and unburned animals.