Premium
STUDIES ON THE ANTIHÆMOLYTIC PROPERTIES OF LECITHIN AND CHOLESTEROL
Author(s) -
Lee JuiShuan,
Tsai Chiao
Publication year - 1942
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1942.sp000862
Subject(s) - oleic acid , digitonin , lecithin , chemistry , glycocholic acid , chromatography , bile acid , cholesterol , cholic acid , biochemistry , enzyme
1. Lecithin is hæmolytic toward oleic acid, taurocholate, and glycocholate, but antihæmolytic to digitonin, crude bile acid preparation, and natural hæmolysin (dog's citrated plasma or serum against rabbit's corpuscles). 2. The antihæmolytic behaviour of lecithin toward crude bile acid is not due to the interaction between taurocholate and glycocholate. 3. The antihæmolytic activity of cholesterol is reinforced by lecithin in all lysin systems except natural hæmolysin, regardless of whether lecithin is inhibitory or acceleratory toward them in the absence of cholesterol. The reinforcement is most pronounced in saponin and digitonin. It is also very evident in crude bile acid and oleic acid. But it is rather feeble in Na‐taurocholate and Na‐glycocholate.