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CHOLECYSTOSTOMY FISTULAE SUITABLE FOR SMALL LABORATORY ANIMALS
Author(s) -
Peacock P. R.
Publication year - 1941
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1941.sp000840
Subject(s) - balloon , medicine , peritoneal cavity , abdominal cavity , tube (container) , surgery , anatomy , nuclear medicine , materials science , composite material
Operations are described for the collection of daily samples of bile from rabbits and fowls: (1) In the operation for rabbits, a collecting balloon is connected with the gall‐bladder by means of a canula and rubber tubing, all of which are placed in the peritoneal cavity. A second collecting tube leads from the balloon to the surface, through a stab wound (fig. 1). Alternatively, a collecting balloon of special shape is placed partly in the peritoneal cavity and partly in the subcutaneous tissues; bile is collected by aspirating the contents of the subcutaneous part of the balloon through the skin (fig. 2). (2) In the case of fowls, the collecting balloon is placed in the subcutaneous tissues, and is connected with the gall‐bladder by means of a single rubber tube and canula. Bile is collected by aspirating the contents of the balloon through the skin (fig. 3). Rabbits and fowls both yield bile samples of about 5 ml. to 15 ml. daily, for about four weeks after this operation, and remain in good health for periods of a year and more.