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LIBERATION OF ACETYLCHOLINE FROM THE PERFUSED CAT'S BRAIN
Author(s) -
Chute A. L.,
Feldberg W.,
Smyth D. H.
Publication year - 1940
Publication title -
quarterly journal of experimental physiology and cognate medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0033-5541
DOI - 10.1113/expphysiol.1940.sp000823
Subject(s) - acetylcholine , liberation , reflex , medicine , endocrinology , chemistry , depression (economics) , anesthesia , biochemistry , in vitro , economics , macroeconomics
The almost completely isolated cat's brain was perfused with 50 per cent. defibrinated blood. The addition of eserine to it produced increased reflex‐excitability with spontaneous movements followed by depression, and caused the appearance in the blood of small amounts of acetylcholine which were liberated from the brain. This liberation was temporarily increased by the injection of KCl.