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THE EFFECT OF OVARIAN EXTRACTS ON THE OXYGEN CONSUMPTION OF THE UTERUS
Author(s) -
Khayyal M. A.,
Scott C. M.
Publication year - 1935
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1935.sp000666
Subject(s) - uterus , hormone , ovary , endocrinology , oxygen , medicine , follicular phase , anterior pituitary , biology , chemistry , organic chemistry
1. Fresh follicular fluid from cows ovaries contains a substance which causes an increase in the oxygen consumption rate of the isolated uterus of mice. 2. This substance is neither cestrin nor the luteal hormone, nor was it found in the blood serum of men and women. 3. Evidence is put forward that this metabolic substance is released from the ovary by the action of the hormones of the anterior pituitary gland, but these latter hormones have no direct action on the oxygen consumption of the isolated uterus. 4. Thyroxine causes a rise in the rate of oxygen consumption of the isolated mouse uterus. 5. Male hormone causes no rise in uterine oxygen consumption. We thank Professor A. J. Clark for his help during this investigation. The expenses were paid by a grant from the Moray Fund of Edinburgh University.