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MODE OF ACTION OF OXYGEN LACK AND CARBON DIOXIDE EXCESS ON RESPIRATION IN THE RABBIT
Author(s) -
Wright Samson
Publication year - 1934
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1934.sp000638
Subject(s) - respiration , carbon dioxide , reflex , stimulation , anesthesia , respiratory system , oxygen , vagus nerve , anatomy , chemistry , medicine , organic chemistry
1. The mode of action of oxygen lack and carbon dioxide excess was examined in the rabbit. 2. Oxygen lack (as in the cat) depresses the “deafferented” respiratory centre and produces reflex stimulation through the sinus, aortic, and vagus nerves. The sinus afferents are probably more important than the others. The vagal fibres employed are probably aortic and not pulmonary in origin. 3. Carbon dioxide excess acts predominantly centrally. Afferent impulses in the sinus nerves are of inconstant importance, but no convincing evidence was obtained that the vago‐aortic nerves participated in any significant degree in the total response.