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THE PHYSIOLOGY OF PREGNANCY IN THE RAT.—I. THE PROLONGATION AND INTERRUPTION OF PREGNANCY
Author(s) -
Hain Annie M.
Publication year - 1932
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1932.sp000573
Subject(s) - corpus luteum , pregnancy , urine , gestation , prolongation , endocrinology , early pregnancy factor , hormone , medicine , anterior pituitary , fetus , physiology , biology , genetics
1. The gestation period in the rat can be prolonged by from 4 to 10 days by (a) administration of anterior pituitary tissue; (b) extract of human pregnancy urine; (c) alkaline extract of pituitary; (d) extract containing “purified” growth hormone. 2. Pregnancy is apt to be interrupted when injection of the urine extract is made in the early stages. 3. The evidence adduced suggests that the pregnant condition is not maintained solely by the corpus luteum, and that parturition is not due merely to degeneration of that body.