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THE ACTION OF HISTAMINE ON THE MOTILITY OF THE LARGE INTESTINE
Author(s) -
Tidmarsh C. J.
Publication year - 1932
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1932.sp000554
Subject(s) - histamine , atropine , motility , small intestine , intestinal motility , action (physics) , chemistry , medicine , large intestine , endocrinology , pharmacology , biology , microbiology and biotechnology , physics , quantum mechanics
1. Histamine injected intravenously evokes a typical motor response in different parts of the large intestine. 2. This action is diminished but not abolished by previous injection of atropine. 3. Histamine in 0·1 to 0·2 per cent. solution of HCl is absorbed from the small and large intestine in sufficiently large amounts to stimulate intestinal motility. I am indebted to professor B. P. Babkin and Professor, J. C. Meakins for advice and assistance.