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THE RESPONSES OF THE BATRACHIAN ALIMENTARY CANAL TO AUTONOMIC DRUGS. XENOPUS LÆVIS (THE SOUTH AFRICAN CLAWED TOAD)—ARECOLINE
Author(s) -
Epstein David
Publication year - 1932
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1932.sp000552
Subject(s) - toad , arecoline , excitatory postsynaptic potential , atropine , xenopus , alimentary tract , anatomy , pilocarpine , biology , chemistry , endocrinology , medicine , neuroscience , inhibitory postsynaptic potential , muscarinic acetylcholine receptor , epilepsy , biochemistry , receptor , gene
1. Arecoline causes contraction of every portion of the alimentary canal of Xenopus lævis (the South African clawed toad), and this is antagonised by atropine. 2. These responses have been interpreted as proving that the whole of the digestive tract of X. lævis receives motor (excitatory) fibres from the parasympathetic system. 3. Arecoline, under certain conditions, is a more suitable drug than pilocarpine for demonstrating the presence of parasympathetic motor (excitatory) fibres.