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BLOOD‐SUGAR CONCENTRATION AND PANCREATIC SECRETION IN THE RABBIT
Author(s) -
Baxter Stewart G.
Publication year - 1932
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1932.sp000547
Subject(s) - endocrinology , medicine , pancreatic juice , tonicity , blood sugar , secretion , insulin , rabbit (cipher) , pancreas , chemistry , diabetes mellitus , statistics , mathematics
1. Insulin hypoglycæmia causes a diminished output of enzymes by the pancreatic gland in a rabbit having vagi intact and spontaneously secreting pancreatic juice. This phenomenon was not observed if the vagi had been cut. 2. The inhibition of the flow of pancreatic juice under the above‐mentioned conditions is not an absolutely constant phenomenon. 3. When the spontaneous pancreatic secretion in the rabbit has been arrested by hypoglycæmia, it may be restored by intravenous injection of a hypertonic glucose solution. This effect is observed when the vagi and splanchnics are intact and also after they have been severed. My thanks are due to Dr B. P. Babkin for helpful criticism throughout this work.