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STUDIES ON THE ARNETH COUNT.—VII. EXPERIMENTAL TUBERCULOSIS IN THE RABBIT
Author(s) -
Ponder Eric,
Flint K. Newstead
Publication year - 1927
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1927.sp000423
Subject(s) - kindness , tuberculosis , tuberculin , rabbit (cipher) , medicine , pathology , immunology , political science , law , mathematics , statistics
1. In experimental tuberculosis in the rabbit there is a left‐handed deflection of the Arneth count, as occurs in the disease in man. 2. There is some evidence for believing that this deflected state is brought about in the first instance by a liberation of cells of Class I. from the marrow, but afterwards maintained by an increased removal from the blood‐stream of the cells of the higher classes. 3. The injection of tuberculin into a tuberculous rabbit has an effect comparable with the injection of thyroid into a normal rabbit. The marrow liberates cells of Class I., which in the course of time develop into cells of the higher classes. This research was carried out under a grant from the Government Grants Committee of the Royal Society. We have to thank Colonel Liston and Dr D. G. S. M'Laughlan for their kindness in supplying us with the bacteriological material.