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STUDIES ON THE ARNETH COUNT.—VI. THE EFFECT OF VARIOUS DRUGS AND EXTRACTS
Author(s) -
Ponder Eric,
Flint K. Newstead
Publication year - 1927
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1927.sp000400
Subject(s) - bone marrow , drug , pharmacology , chemistry , medicine , physiology , toxicology , biology
The results recorded in this paper show that many substances besides thyroid extract and thyroxin deflect the Arneth count in the rabbit. Each one of these substances produces at the same time a polymorph leucocytosis, and we may conclude that the substances which deflect the count do so by stimulating the bone marrow and thus causing an outpouring of the younger forms of polymorph, which have simple nuclear configuration. Although representative experiments only are given, the results have been arrived at by the consideration of the effects on from three to six animals in the case of each drug.