Premium
STUDIES ON THE ARNETH COUNT.—IV. THE DEFLECTION OF THE COUNT BY THYROID INJECTIONS
Author(s) -
Ponder Eric
Publication year - 1926
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1926.sp000386
Subject(s) - thyroid , medicine , circulation (fluid dynamics) , chemistry , physics , mechanics
1. By means of a single injection of thyroid a deflection of the Arneth count is produced, a large number of cells of Class I. being introduced into the circulation. The subsequent changes in the count are followed, and it is shown that the cells of Class I. develop in the blood‐stream into cells of Class II., these into cells of Class III., and so on until Class V. is reached. 2. In animals under the conditions of these experiments, the cells leave the blood‐stream principally from Classes IV. and V. 3. In the experimental animals used, the duration of time which a polymorph spends in the circulation is from two to three weeks. About 10 7 polymorphs are produced by the marrow per diem. This research was carried out under a grant from the Government Grants Committee of the Royal Society, and some of the earlier experimental work under a grant from the Medical Research Council. I have to thank Mr K. Newstead Flint for his careful carrying out of much of the routine work associated with this investigation.