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THE EFFECT OF ADRENALINE ON LEFT AURICULAR PRESSURE
Author(s) -
McDowall R. J. S.
Publication year - 1923
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1923.sp000292
Subject(s) - ventricle , medicine , constriction , left atrial pressure , cardiology , anesthesia , vagus nerve , action (physics) , blood pressure , stimulation , physics , quantum mechanics
Experiments have been carried out which demonstrate the different factors which affect the pressure changes in the left auricle when adrenaline is injected. These are seen to be the action of the vagus, of the right ventricle, of the pulmonary vessels, of the left ventricle, of the anaesthetic and of the artificial respiration. After the vagi have been cut it is usual to get a fall in left auricular pressure with adrenaline. This fall is shown to be due largely to constriction of the pulmonary vessels by the adrenaline ; often, but not always, supplemented by increased action of the left ventricle. This research was assisted by a grant from the British Medical Association. I wish to thank Messrs, Parke, Davis and Co., for their kindness in providing me with adrenaline for the investigation.