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OBSERVATIONS ON THE ISOLATED PYLORIC SEGMENT AND ON ITS SECRETION
Author(s) -
Lim Robert K. S.,
Dott Norman M.
Publication year - 1923
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1923.sp000286
Subject(s) - pouch , pylorus , pepsin , peptic , secretion , chemistry , medicine , stomach , biology , anatomy , peptic ulcer , biochemistry , enzyme
1. The operative methods for isolating the pyloric segment and forming it into a pouch, are described. 2. The secretion of the pyloric pouch is viscid, slightly alkaline and definitely proteolytic. 3. The proteolytic action of the pyloric juice is not due to bacterial contamination, nor to the inclusion of peptic cells in the wall of the pyloric pouch, but to the presence of a ferment. 4. The ferment secreted by the mucoid cells of the pylorus is only 1/25 as active as pepsin secreted by the peptic cells of the fundus, and has no associated rennin action.