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A METHOD FOR RECORDING GASTRIC SECRETION IN ACUTE EXPERIMENTS ON NORMAL ANIMALS
Author(s) -
Lim Robert K. S.
Publication year - 1922
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1922.sp000279
Subject(s) - stomach , cannula , secretion , pylorus , pepsin , gastric secretion , chemistry , medicine , surgery , biochemistry , enzyme
A method for recording gastric secretion in normal anaesthetised animals is described. It depends on the use of a perforated glass cannula (introduced into the stomach through the pylorus) to drain the stomach of its juice, which is allowed to activate a drop‐recorder after its escape from the organ. A balloon is also inserted into the stomach to serve as a control of motor changes. The method permits of observations being made on the latent period, the duration and the quantity of secretion after the introduction of a suitable excitant. The juice thus obtained invariably contains free HCL and pepsin.