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STUDIES ON THE ENDOCRINE GLANDS:—II.: THE RELATIONS OF THE PITUITARY BODY WITH THE THYROID AND PARATHYROID AND CERTAIN OTHER ENDOCRINE ORGANS IN THE RAT
Author(s) -
Kojima Masaharu
Publication year - 1917
Publication title -
quarterly journal of experimental physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 101
eISSN - 1469-445X
pISSN - 0370-2901
DOI - 10.1113/expphysiol.1917.sp000244
Subject(s) - pars intermedia , thyroidectomy , endocrine system , parathyroidectomy , parathyroid gland , hyaline , thyroid , pituitary gland , endocrine gland , anterior pituitary , vesicle , cyst , chromophobe cell , anatomy , pathology , medicine , endocrinology , biology , parathyroid hormone , hormone , calcium , clear cell , membrane , renal cell carcinoma , genetics
The effects of thyroidectomy—which was only partial, since it was desired to leave the parathyroids in situ—have been to cause changes in the pituitary consisting in the accumulation of colloid between the cells of the pars anterior, such as has been described by previous investigators, and an especial development of oxyphil cells, as well as the appearance of many swollen—possibly degenerating—cells, some of which are seen to surround clear vesicles. In the case described there was a cyst‐like expansion of the intraglandular cleft in the pars anterior, but whether the result of the thyroidectomy or not, cannot be stated. The pars intermedia was thickened, and contained many vesicles, surrounded by cells, and occupied by masses of hyaline substance. These vesicles extend here and there into the pars nervosa. The chief effect of partial parathyroidectomy was to produce an œdematous condition of all parts of the pituitary. Oxyphil cells appeared more abundantly than usual in the pars anterior, but there were no such striking changes in the gland as are caused by thyroidectomy.