Open AccessPrevalence and incidence of congenital anomalies amongst babies born to women with sickle cell disease and exposed to hydroxyurea during pregnancy: a systematic review protocol
Author(s) -
Stephen Gwer,
Kennedy Onyango
Publication year - 2018
Publication title -
jbi database of systematic reviews and implementation reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.405
H-Index - 21
ISSN - 2202-4433
DOI - 10.11124/jbisrir-2017-003548
Subject(s) - medicine , pregnancy , incidence (geometry) , pediatrics , disease , obstetrics , genetics , biology , physics , optics
What is the prevalence and incidence of congenital anomalies among babies born to women with sickle cell disease (SCD) and who have been exposed to hydroxyurea (HU) therapy at any time in their pregnancy?The objective of this review is to identify the proportion of babies born with congenital anomalies among babies born to mothers with SCD who have been exposed to HU therapy at any point during pregnancy and to describe the specific types of congenital anomalies encountered.