Open AccessFluid biomarkers of white matter hyperintensities in cerebrovascular disease and neurodegeneration: a systematic review protocol
Author(s) -
Chloe Anastassiadis,
Anna Vasilevskaya,
Melisa Gumus,
Alexandra Gomes dos Santos,
Maria Carmela Tartaglia
Publication year - 2021
Publication title -
jbi evidence synthesis
Language(s) - English
Resource type - Journals
ISSN - 2689-8381
DOI - 10.11124/jbies-20-00210
Subject(s) - hyperintensity , medicine , etiology , disease , white matter , biomarker , systematic review , meta analysis , neurodegeneration , pathology , neuroimaging , intensive care medicine , bioinformatics , medline , magnetic resonance imaging , psychiatry , radiology , biology , biochemistry
The goal of this systematic review is to evaluate the association between fluid biomarkers and white matter hyperintensities (WMH) in cerebrovascular disease and neurodegenerative disorders. While previous research has examined the etiology of WMH in specific diseases, we propose a comprehensive framework encompassing WMH of both vascular and non-vascular origin.