Open AccessSIMULTANEOUS ELECTROCHEMICAL DETECTION OF ASCORBIC ACID, DOPAMINE, AND URIC ACID AT MAGNETIC NANOPARTICLES/REDUCED GRAPHENE OXIDE MODIFIED ELECTRODE
Author(s) -
Azleen Rashidah Mohd Rosli,
Farhanini Yusoff,
Saw Hong Loh,
Hanis Mohd Yusoff,
Muhammad Mahadi Abdul Jamil,
Shazrul Hasry Shamsudin
Publication year - 2021
Publication title -
jurnal teknologi/jurnal teknologi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.191
H-Index - 22
eISSN - 2180-3722
pISSN - 0127-9696
DOI - 10.11113/jurnalteknologi.v83.15161
Subject(s) - ascorbic acid , graphene , detection limit , cyclic voltammetry , dielectric spectroscopy , materials science , fourier transform infrared spectroscopy , differential pulse voltammetry , electrode , analytical chemistry (journal) , electrochemical gas sensor , scanning electron microscope , nuclear chemistry , electrochemistry , inorganic chemistry , chemistry , chemical engineering , nanotechnology , chromatography , food science , composite material , engineering
A magnetic nanoparticles/reduced graphene oxide modified glassy carbon electrode (MNP/rGO/GCE) was fabricated via one-step facile synthesis route for the simultaneous determination of ascorbic acid (AA), dopamine (DA), along with uric acid (UA). A series of diseases and disorders has been associated with irregular levels of these respective analytes, thus early detection is highly crucial. Physical and electrochemical characterization of the modified electrode was conducted by using Scanning Electron Microscopy (SEM), Fourier Transform Infrared (FTIR) analysis, X-Ray Diffraction (XRD) analysis and Brauneur-Emmet-Teller (BET), Cyclic Voltammetry (CV) and Electron Impedance Spectroscopy (EIS). The results obtained confirmed the formation of MNP/rGO composite. Differential pulse voltammetry (DPV) of MNP/rGO/GCE displays three well-defined peaks which associated to AA, DA and UA, respectively. The response towards DA is linear in the concentration range of 15 nM to 100 µM with a detection limit of 0.19 nM while a response to AA and UA is also linear in the concentration range of 10 µM to 100 µM with a limit of detection 0.22 µM and 45 nM respectively. The proposed modified electrode offers a good response towards simultaneous detection of three different electroactive species with excellent electron transfer rate, great capacitance and ideal diffusive control behavior.