Open AccessAntibacterial and Cytotoxicity Analyses on Aloe vera Body Soap
Author(s) -
Alex Lo Zhen Kai,
Nurizzati Mohd Daud,
Norhidayu Muhamad Zain
Publication year - 2022
Publication title -
journal of human centered technology
Language(s) - English
Resource type - Journals
ISSN - 2821-3467
DOI - 10.11113/humentech.v1n1.13
Subject(s) - aloe vera , antibacterial activity , cytotoxicity , traditional medicine , microbiology and biotechnology , mtt assay , minimum inhibitory concentration , escherichia coli , chemistry , biology , bacteria , food science , in vitro , antimicrobial , medicine , biochemistry , genetics , gene
Aloe vera is a well-known succulent plant and it is often used to moisturise and sooth the skin. In this study, Aloe vera is incorporated into natural soap to investigate the antibacterial properties and cytotoxicity of the samples. The antibacterial properties of the Aloe vera sample was determined by performing zone inhibition and bacterial colony test on Escherichia coli (E. coli). The cell viability test was conducted with human skin fibroblast cells through MTT assay. The Aloe vera samples showed antibacterial properties through the presence of inhibition zones and in the bacterial colony analysis, the Aloe vera samples have inhibitory effect against E. coli with a bacterial retardation percentage of 31.97±0.90%. The cell viability percentage of 95.30±11.16% was found on the Aloe vera sample with normal cell morphology. These results testified that the Aloe vera sample was biocompatible and possessed antibacterial properties which is suitable to be incorporated in skin products.