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Evolution of highly pathogenic H7N3 avian influenza viruses in Mexico
Author(s) -
Trovão Nídia Sequeira,
Talavera Guadalupe Ayora,
Nelson Martha I.,
Perez de la Rosa Juan Diego
Publication year - 2020
Publication title -
zoonoses and public health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.87
H-Index - 65
eISSN - 1863-2378
pISSN - 1863-1959
DOI - 10.1111/zph.12673
Subject(s) - highly pathogenic , clade , influenza a virus subtype h5n1 , biology , virology , avian influenza virus , host (biology) , 28s ribosomal rna , virus , phylogenetics , rna , genetics , gene , ribosome
Highly pathogenic H7N3 influenza A viruses have persisted in poultry in Mexico since 2012, diversifying into multiple lineages that have spread to three Mexican states, as of 2016. The H7N3 viruses segregate into three distinct clades that are geographically structured. All 2016 viruses are resistant to adamantane antiviral drugs and have an extended 24‐nucleotide insertion at the HA cleavage site that was acquired from host 28S ribosomal RNA.